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De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017.

G. Curigliano,H. Burstein,51 Authors,Bo Xu

2017 · DOI: 10.1093/annonc/mdx806
Annals of Oncology · 494 Citations

TLDR

The Panel favored several interventions that may reduce surgical morbidity, including acceptance of 2mm margins for DCIS, the resection of residual cancer in women undergoing neoadjuvant therapy, and the preference for neoad juvant therapy in HER2 positive and triple-negative, stage II and III breast cancer.