Contribution of the α1-GABAA receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists
Contribution of the α1-GABAA receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists
F. Crestani,R. Assandri,2 Authors,U. Rudolph
2002 · DOI: 10.1016/S0028-3908(02)00159-4
69 Citations
TLDR
The α1-GABAA receptors are identified as the molecular targets for the allosteric modulation by benzodiazepine site ligands in either direction with regard to the behavioral outputs, sedation/motor stimulation and anticonvulsion/proconvulsion.