Chronic 5‐HT6 receptor modulation by E‐6837 induces hypophagia and sustained weight loss in diet‐induced obese rats
Chronic 5‐HT6 receptor modulation by E‐6837 induces hypophagia and sustained weight loss in diet‐induced obese rats
A. Fisas,X. Codony,7 Authors,P. Pauwels
2006 · DOI: 10.1038/sj.bjp.0706807
British Journal of Pharmacology · 93 Citations
TLDR
Results show that the 5‐HT6 receptor partial agonist, E‐6837, is a promising new approach to the management of obesity with the potential to produce greater sustained weight loss than sibutramine.