Celecoxib extends C. elegans lifespan via inhibition of insulin‐like signaling but not cyclooxygenase‐2 activity
Celecoxib extends C. elegans lifespan via inhibition of insulin‐like signaling but not cyclooxygenase‐2 activity
T. Ching,Wei-Chung Chiang,Ching-shih Chen,A. Hsu
2011 · DOI: 10.1111/j.1474-9726.2011.00688.x
Aging Cell · 48 Citations
TLDR
It is reported that celecoxib, a nonsteroidal anti‐inflammatory drug widely used to treat pain and inflammation, extends Caenorhabditis elegans lifespan and delays the age‐associated physiological changes, such as motor activity decline.