UPDF AI

Capacitative Ca2+ Entry via Orai1 and Stromal Interacting Molecule 1 (STIM1) Regulates Adenylyl Cyclase Type 8

Agnés C. L. Martin,D. Willoughby,5 Authors,D. Cooper

2009 · DOI: 10.1124/mol.108.051748
Molecular Pharmacology · 79 Citations

TLDR

Together, the data indicate that Orai1 and STIM1 can be integral components of the cAMP and CCE microdomain associated with adenylyl cyclase type 8, and also indicate that AC8 is believed to be closely associated with the source of CCE.