Calcium binding to tandem repeats of EGF‐like modules. Expression and characterization of the EGF‐like modules of human Notch‐1 implicated in receptor‐ligand interactions
Calcium binding to tandem repeats of EGF‐like modules. Expression and characterization of the EGF‐like modules of human Notch‐1 implicated in receptor‐ligand interactions
M. Rand,A. Lindblom,2 Authors,J. Stenflo
1997 · DOI: 10.1002/PRO.5560061002
Protein Science · 64 Citations
TLDR
The highest affinity sites in hNEGF11‐12 and hN EGF10‐13 had 10 to 100‐fold higher affinity than reported for EGF32‐33 and EGF25‐31, respectively, from fibrillin‐1, a connective tissue protein with 43 cbEGF modules.