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Caffeic and chlorogenic acids inhibit key enzymes linked to type 2 diabetes (in vitro): a comparative study

G. Oboh,O. Agunloye,2 Authors,A. Ademiluyi

2015 · DOI: 10.1515/jbcpp-2013-0141
Journal of Basic and Clinical Physiology and Pharmacology · 323 Citations

TLDR

The esterification of caffeic acid with quinic acid, producing chlorogenic acid, reduces their ability to inhibit α-amylase and α-glucosidase activities, which could be part of the possible mechanism by which the phenolic acids exert their antidiabetic effects.