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Butyrate enhances antibacterial effects while suppressing other features of alternative activation in IL-4-induced macrophages.

M. Fernando,A. Saxena,J. Reyes,D. McKay

2016 · DOI: 10.1152/ajpgi.00440.2015
56 Citations

TLDR

The demonstration that butyrate promotes phagocytosis in M(IL-4)s that can limit T-cell production of IL-17A reveals novel aspects of bacterial-host interaction in the regulation of intestinal homeostasis.