Biofilms in vitro and in vivo: do singular mechanisms imply cross‐resistance?
Biofilms in vitro and in vivo: do singular mechanisms imply cross‐resistance?
P. Gilbert,D. Allison,A. McBain
2002 · DOI: 10.1046/j.1365-2672.92.5s1.5.x
322 Citations
TLDR
Sublethal concentrations of the antibacterial and antifungal agent triclosan can select for resistant mutants in Escherichia coli and this agent specifically targets the enzyme enoyl reductase that is involved in lipid biosynthesis.
