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Biofilms in vitro and in vivo: do singular mechanisms imply cross‐resistance?

P. Gilbert,D. Allison,A. McBain

2002 · DOI: 10.1046/j.1365-2672.92.5s1.5.x
322 Citations

TLDR

Sublethal concentrations of the antibacterial and antifungal agent triclosan can select for resistant mutants in Escherichia coli and this agent specifically targets the enzyme enoyl reductase that is involved in lipid biosynthesis.