Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: Involvement of NF-κB signaling pathway
Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: Involvement of NF-κB signaling pathway
Qin Jiang,Peiqing Liu,7 Authors,Heqing Huang
2011 · DOI: 10.1016/j.mce.2010.07.023
Molecular and Cellular Endocrinology · 136 Citations
TLDR
Berberine significantly repressed LPS-induced cell proliferation and FN expression in rat MCs through inhibiting the activation of NF-κB signaling pathway and protein expression of its downstream inflammatory mediators.