Bacteria‐ and host‐derived mechanisms to control intestinal epithelial cell homeostasis: Implications for chronic inflammation
Bacteria‐ and host‐derived mechanisms to control intestinal epithelial cell homeostasis: Implications for chronic inflammation
T. Clavel,D. Haller
2007 · DOI: 10.1002/ibd.20174
Inflammatory Bowel Diseases · 111 Citations
TLDR
It is suggested that disturbances in the homeostasis between bacteria‐ and host‐derived signals at the epithelial cell level lead to a break in the intestinal barrier function and to the development of mucosal immune disorders in genetically susceptible hosts.