Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family
Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family
Kefeng Lu,Ivan Psakhye,S. Jentsch
2014 · DOI: 10.1016/j.cell.2014.05.048
Cell · 338 Citations
TLDR
It is proposed that CUET proteins play a critical and ancient role in autophagic clearance of cytotoxic protein aggregates.