Autolysosomal β‐catenin degradation regulates Wnt‐autophagy‐p62 crosstalk
Autolysosomal β‐catenin degradation regulates Wnt‐autophagy‐p62 crosstalk
Katy J. Petherick,A. Williams,8 Authors,A. Greenhough
2013 · DOI: 10.1038/emboj.2013.123
EMBO Journal · 287 Citations
TLDR
Findings reveal a regulatory feedback mechanism that place β‐catenin at a key cellular integration point coordinating proliferation with autophagy, with implications for targeting these pathways for cancer therapy.
