An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle.
An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle.
J. Little,A. Safdar,2 Authors,M. Gibala
2011 · DOI: 10.1152/ajpregu.00538.2010
American Journal of Physiology. Regulatory Integrative and Comparative Physiology · 377 Citations
TLDR
Findings support the hypothesis that an acute bout of low-volume HIT activates mitochondrial biogenesis through a mechanism involving increased nuclear abundance of PGC-1α.