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Alteration of Y-box binding protein-1 expression modifies the response to endocrine therapy in estrogen receptor-positive breast cancer

Tokiko Ito,Shinobu Kamijo,3 Authors,Ken-ichi Ito

2012 · DOI: 10.1007/s10549-011-1731-8
Breast Cancer Research and Treatment · 29 Citations

TLDR

The data suggest that alteration of YB-1 may modify the crosstalk between the ER pathway and HER2 pathway in ER-positive breast cancer cells, and consequently, may alter the response to endocrine therapy in estrogen receptor (ER)-positive breast cancers.