Akt signalling through GSK‐3β, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy
Akt signalling through GSK‐3β, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy
B. Léger,Romain Cartoni,8 Authors,A. Russell
2006 · DOI: 10.1113/jphysiol.2006.116715
Journal of Physiology · 380 Citations
TLDR
It is demonstrated, for the first time in human skeletal muscle, that the regulation of Akt and its downstream signalling pathways GSK‐3β, mTOR and Foxo1 are associated with both the skeletal muscle hypertrophy and atrophy processes.