Agonistic effects of the beta-carboline DMCM revealed in GABA(A) receptor gamma 2 subunit F77I point-mutated mice.
Agonistic effects of the beta-carboline DMCM revealed in GABA(A) receptor gamma 2 subunit F77I point-mutated mice.
E. Leppä,O. Vekovischeva,4 Authors,E. Korpi
2005 · DOI: 10.1016/J.NEUROPHARM.2004.11.007
Neuropharmacology · 24 Citations
TLDR
In vivo DMCM produced modest anxiolytic-like effects in gamma2I77 mice as assessed by elevated plus maze and staircase tests, but no motor impairment was found in the rotarod test.