Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells
Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells
Sergey Ryzhov,S. Novitskiy,5 Authors,I. Feoktistov
2011 · DOI: 10.4049/jimmunol.1101225
Journal of Immunology · 251 Citations
TLDR
It is proposed that generation of adenosine by CD73 expressed at high levels on granulocytic MDSCs may promote their expansion and facilitate their immunosuppressive activity.