Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37
Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37
D. Sarhan,K. Hippen,10 Authors,Jeffrey S. Miller
2018 · DOI: 10.1158/2326-6066.CIR-17-0498
Cancer immunology research · 101 Citations
TLDR
It is shown that canonical NK cells are highly susceptible to Treg-mediated suppression, in contrast to highly resistant CD57+ FcϵRγ−NKG2C+ adaptive (CD56+CD3−) NK cells that expand in cytomegalovirus exposed individuals.