A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells.
A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells.
Bastian Hoechst,Lars A. Ormandy,5 Authors,F. Korangy
2008 · DOI: 10.1053/j.gastro.2008.03.020
Gastroenterology · 807 Citations
TLDR
A new mechanism by which myeloid-derived suppressor cells exert their immunosuppressive function is proposed, through the induction of CD4(+)CD25(+)Foxp3(+) regulatory T cells in cocultured CD 4(+) T cells.