A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
K. Cadwell,John Y. Liu,15 Authors,H. Iv
2008 · DOI: 10.1038/nature07416
Nature · 1,566 Citations
TLDR
ATG16L1, and probably the process of autophagy, have a role within the intestinal epithelium of mice and Crohn’s disease patients by selective effects on the cell biology and specialized regulatory properties of Paneth cells.