A human monoclonal antibody blocking SARS-CoV-2 infection
A human monoclonal antibody blocking SARS-CoV-2 infection
Chunyan Wang,Wentao Li,7 Authors,B. Bosch
TLDR
A human monoclonal antibody is reported capable of neutralizing both authentic SARS-CoV and SARS -CoV-2 by targeting a common epitope on these viruses.
Abstract
The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19. Vaccines and targeted therapeutics for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are currently lacking. Here, the authors report a human monoclonal antibody capable of neutralizing both authentic SARS-CoV and SARS-CoV-2 by targeting a common epitope.