A Predictably Selective Aliphatic C–H Oxidation Reaction for Complex Molecule Synthesis
A Predictably Selective Aliphatic C–H Oxidation Reaction for Complex Molecule Synthesis
Mark S. Chen,M. White
2007 · DOI: 10.1126/SCIENCE.1148597
Science · 1,053 Citations
TLDR
An iron (Fe)–based small molecule catalyst that uses hydrogen peroxide (H2O2) to oxidize a broad range of substrates and Predictable selectivity is achieved solely on the basis of the electronic and steric properties of the C–H bonds, without the need for directing groups.
