Vasculopathy in patients with Fabry disease: current controversies and research directions.
Vasculopathy in patients with Fabry disease: current controversies and research directions.
S. Rombach,Th. B. Twickler,3 Auteurs,C. Hollak
2010 · DOI: 10.1016/j.ymgme.2009.10.004
Molecular Genetics and Metabolism · 144 citaten
TLDR
A hypothesis on the evolution of arterial complications in Fabry disease is proposed and it is hypothesized that upregulation of local renin angiotensine systems may occur in the presence of a hyperdynamic circulation in combination with a less compliant vascular wall.