Metabolic Modeling of Dynamic 13C NMR Isotopomer Data in the Brain In Vivo: Fast Screening of Metabolic Models Using Automated Generation of Differential Equations
Metabolic Modeling of Dynamic 13C NMR Isotopomer Data in the Brain In Vivo: Fast Screening of Metabolic Models Using Automated Generation of Differential Equations
Brice Tiret,A. Shestov,J. Valette,P. Henry
2015 · DOI: 10.1007/s11064-015-1748-1
Neurochemical Research · 13 citaten
TLDR
A new approach is presented that allows automatic implementation of multi-compartment metabolic models capable of fitting any number of 13C isotopomer curves in the brain, and makes it possible to quickly modify and test new models to best describe the experimental data.