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FUS-dependent liquid–liquid phase separation is important for DNA repair initiation

B. Levone,S. C. Lenzken,12 著者,S. Barabino

2021 · DOI: 10.1083/jcb.202008030
Journal of Cell Biology · 141 件の引用

TLDR

FUS-dependent liquid–liquid phase separation is a critical process in the early activation of the DNA damage response and in the recruitment of key proteins, which facilitates the proper assembly of double-strand break repair complexes.

要旨

FUS-dependent liquid–liquid phase separation is a critical process in the early activation of the DNA damage response and in the recruitment of key proteins, which facilitates the proper assembly of double-strand break repair complexes.