Metabolic regulation of gene expression through histone acylations
Metabolic regulation of gene expression through histone acylations
Benjamin R. Sabari,Di Zhang,C. Allis,Yingming Zhao
2016 · DOI: 10.1038/nrm.2016.140
Nature reviews. Molecular cell biology · 826 citazioni
TLDR
A model is proposed to explain the present understanding of how differential histone acylation is regulated by the metabolism of the different acyl-CoA forms, which in turn modulates the regulation of gene expression.