TGF-β: the master regulator of fibrosis
TGF-β: the master regulator of fibrosis
Xiao-ming Meng,D. Nikolic-Paterson,H. Lan
2016 · DOI: 10.1038/nrneph.2016.48
Nature Reviews Nephrology · 引用 2,754 次
TLDR
Studies over the past 5 years have identified additional mechanisms that regulate the action of TGF-β1/Smad signalling in fibrosis, including short and long noncoding RNA molecules and epigenetic modifications of DNA and histone proteins.