H3K4me1 facilitates promoter-enhancer interactions and gene activation during embryonic stem cell differentiation.
H3K4me1 facilitates promoter-enhancer interactions and gene activation during embryonic stem cell differentiation.
Naoki Kubo,P. B. Chen,3 作者,Bing Ren
2024 · DOI: 10.1016/j.molcel.2024.02.030
Molecules and Cells · 引用 45 次
TLDR
Observations implicate KMT2B in the catalysis of H3K4me1 at enhancers and provide additional support for an active role of H3K4me1 in enhancer-promoter interactions and transcription in mammalian cells.