FUS-dependent liquid–liquid phase separation is important for DNA repair initiation
FUS-dependent liquid–liquid phase separation is important for DNA repair initiation
B. Levone,S. C. Lenzken,12 作者,S. Barabino
2021 · DOI: 10.1083/jcb.202008030
Journal of Cell Biology · 引用 141 次
TLDR
FUS-dependent liquid–liquid phase separation is a critical process in the early activation of the DNA damage response and in the recruitment of key proteins, which facilitates the proper assembly of double-strand break repair complexes.
摘要
FUS-dependent liquid–liquid phase separation is a critical process in the early activation of the DNA damage response and in the recruitment of key proteins, which facilitates the proper assembly of double-strand break repair complexes.