Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Bernd Zetsche,J. Gootenberg,9 作者,Feng Zhang
2015 · DOI: 10.1016/j.cell.2015.09.038
Cell · 引用 3,965 次
TLDR
It is demonstrated that Cpf1 mediates robust DNA interference with features distinct from Cas9, and this mechanism of interference broadens the understanding of CRISPR-Cas systems and advances their genome editing applications.