Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
D. Baker,Tobias Wijshake,5 作者,J. Deursen
2011 · DOI: 10.1038/nature10600
Nature · 引用 3,251 次
TLDR
Data indicate that cellular senescence is causally implicated in generating age-related phenotypes and that removal of senescent cells can prevent or delay tissue dysfunction and extend healthspan.