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Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
M. Plattén,E. Nollen,2 Auteurs,C. Opitz
2019 · DOI: 10.1038/s41573-019-0016-5
Nature reviews. Drug discovery · 1,143 citations
TLDR
An overview of the physiological and pathophysiological roles of tryptophan metabolism is provided, focusing on the clinical potential and challenges associated with targeting this pathway.