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The gut microbiota as an environmental factor that regulates fat storage.
The gut microbiota as an environmental factor that regulates fat storage.
F. Bäckhed,Hao Ding,5 Auteurs,J. Gordon
2004 · DOI: 10.1073/PNAS.0407076101
Proceedings of the National Academy of Sciences of the United States of America · 5,896 citations
TLDR
It is found that conventionalization of adult germ-free (GF) C57BL/6 mice with a normal microbiota harvested from the distal intestine of conventionally raised animals produces a 60% increase in body fat content and insulin resistance within 14 days despite reduced food intake.