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Metabolic regulation of gene expression through histone acylations
Metabolic regulation of gene expression through histone acylations
Benjamin R. Sabari,Di Zhang,C. Allis,Yingming Zhao
2016 · DOI: 10.1038/nrm.2016.140
Nature reviews. Molecular cell biology · 826 citations
TLDR
A model is proposed to explain the present understanding of how differential histone acylation is regulated by the metabolism of the different acyl-CoA forms, which in turn modulates the regulation of gene expression.