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Identification of potent antimicrobial peptides via a machine-learning pipeline that mines the entire space of peptide sequences
Identification of potent antimicrobial peptides via a machine-learning pipeline that mines the entire space of peptide sequences
Jun-jie Huang,Yanchao Xu,8 Auteurs,Jian Ji
2023 · DOI: 10.1038/s41551-022-00991-2
Nature Biomedical Engineering · 150 citations
TLDR
A machine-learning pipeline that mines the entire space of polypeptide-chain sequences can identify potent antimicrobial peptides by integrating tasks that gradually narrow down the search space.