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Cell2location maps fine-grained cell types in spatial transcriptomics

Vitalii Kleshchevnikov,Artem Shmatko,17 Auteurs,O. Bayraktar

2022 · DOI: 10.1038/s41587-021-01139-4
Nature Biotechnology · 721 citations

TLDR

A Bayesian model that can resolve fine-grained cell types in spatial transcriptomic data and create comprehensive cellular maps of diverse tissues is presented, enabling the integration of single-cell and spatial transcriptomics with higher sensitivity and resolution than existing tools.