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miR‐142‐3p restricts cAMP production in CD4+CD25− T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA
miR‐142‐3p restricts cAMP production in CD4+CD25− T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA
Bo Huang,Jie Zhao,5 Autores,Zuo-hua Feng
2009 · DOI: 10.1038/embor.2008.224
EMBO Reports · 275 citas
TLDR
This work shows that miR‐142‐3p regulates the production of cAMP by targeting adenylyl cyclase (AC) 9 messenger RNA in CD4+CD25− T cells and CD4-CD25+ TREG cells, and suggests that the microRNA controlling AC expression might restrict the final level of camp in various types of cells.
