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Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers.

M. Flockhart,L. C. Nilsson,3 Autores,F. Larsen

2021 · DOI: 10.1016/j.cmet.2021.02.017
Cell Metabolism · 187 citas

TLDR

A striking reduction in intrinsic mitochondrial function was found that coincided with a disturbance in glucose tolerance and insulin secretion during an intervention with a progressively increasing exercise load over 4 weeks.