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FUS-dependent liquid–liquid phase separation is important for DNA repair initiation
FUS-dependent liquid–liquid phase separation is important for DNA repair initiation
B. Levone,S. C. Lenzken,12 Autores,S. Barabino
2021 · DOI: 10.1083/jcb.202008030
Journal of Cell Biology · 141 citas
TLDR
FUS-dependent liquid–liquid phase separation is a critical process in the early activation of the DNA damage response and in the recruitment of key proteins, which facilitates the proper assembly of double-strand break repair complexes.
Resumen
FUS-dependent liquid–liquid phase separation is a critical process in the early activation of the DNA damage response and in the recruitment of key proteins, which facilitates the proper assembly of double-strand break repair complexes.
