Fisetin is a senotherapeutic that extends health and lifespan
Fisetin is a senotherapeutic that extends health and lifespan
Matthew J. Yousefzadeh,Yi Zhu,19 Autoren,L. Niedernhofer
2018 · DOI: 10.1016/j.ebiom.2018.09.015
EBioMedicine · 773 Zitierungen
TLDR
Administration of fisetin to wild-type mice late in life restored tissue homeostasis, reduced age-related pathology, and extended median and maximum lifespan, suggesting the feasibility to translation to human clinical studies.