DeepConsensus improves the accuracy of sequences with a gap-aware sequence transformer
DeepConsensus improves the accuracy of sequences with a gap-aware sequence transformer
Gunjan Baid,Daniel E. Cook,16 作者,Andrew Carroll
2022 · DOI: 10.1038/s41587-022-01435-7
Nature Biotechnology · 引用数 114
TLDR
Deep learning reduces errors in sequences from PacBio HiFi reads by using an alignment-based loss to train a gap-aware transformer–encoder for sequence correction, which reduces read errors by 42%.