Spermidine induces autophagy by inhibiting the acetyltransferase EP300
Spermidine induces autophagy by inhibiting the acetyltransferase EP300
F. Pietrocola,F. Pietrocola,16 作者,G. Kroemer
2014 · DOI: 10.1038/cdd.2014.215
Cell Death and Differentiation · 引用数 269
TLDR
Results support the idea that EP300 acts as an endogenous repressor of autophagy and that potent Autophagy inducers including spermidine de facto act as EP300 inhibitors.