Wnt signaling and cellular metabolism in osteoblasts
Wnt signaling and cellular metabolism in osteoblasts
Courtney M. Karner,Fanxin Long
2017 · DOI: 10.1007/s00018-016-2425-5
253 Citações
TLDR
Recent studies have uncovered that Wnt signaling directly reprograms cellular metabolism by stimulating aerobic glycolysis, glutamine catabolism as well as fatty acid oxidation in osteoblast-lineage cells, revealing an important regulatory axis between bone anabolic signals and cellular bioenergetics.