Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers.
Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers.
M. Flockhart,L. C. Nilsson,3 Autores,F. Larsen
2021 · DOI: 10.1016/j.cmet.2021.02.017
Cell Metabolism · 187 Citações
TLDR
A striking reduction in intrinsic mitochondrial function was found that coincided with a disturbance in glucose tolerance and insulin secretion during an intervention with a progressively increasing exercise load over 4 weeks.