Channelrhodopsin-2, a directly light-gated cation-selective membrane channel
Channelrhodopsin-2, a directly light-gated cation-selective membrane channel
G. Nagel,T. Szellas,6 Autores,E. Bamberg
2003 · DOI: 10.1073/pnas.1936192100
Proceedings of the National Academy of Sciences of the United States of America · 2,537 Citações
TLDR
It is demonstrated by functional expression, both in oocytes of Xenopus laevis and mammalian cells, that ChR2 is a directly light-switched cation-selective ion channel, and may be used to depolarize small or large cells, simply by illumination.